Upgrading Windows Vista to Windows 10 requires a clean installation, which means that everything on your computer will be erased. How to create a full backup on Windows Vista You can get a copy of Windows 10 Home or Windows 10 Pro at the Microsoft Store.Īdditionally, you'll need a USB flash drive with 8GB of storage to create a bootable media. Once you know that your device can handle the new OS, you'll need to purchase a genuine copy of Windows 10.